Neural Stem Cells
Neural stem cells have been identified in nearly all regions of the developing mouse, rat and human central nervous system (CNS) and in specialized neurogenic regions of the mature CNS.The identification of CNS-resident NSCs and the discovery that adult somatic cells from mouse and human can be reprogrammed to a pluripotent state, and then directed to differentiate into neural cell types, has opened the door to new therapeutic avenues aimed at replacing lost or damaged CNS cells.
We've created these resources to support your neural stem cell research.
Neural Stem Cell Culture Systems - Neurosphere vs. Adherent Monolayer Culture
This webinar provides an overview of the neurosphere and adherent monolayer methods to culture neural stem and progenitor cells. Technical aspects and details associated with performing each of the culture methods are discussed. In addition, data comparing the two methods is presented.
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How to Choose the Right Neural Cell Culture Model for Your Research QuestionIn this Innovation Showcase talk from ISSCR 2022, our Associate Director of Neural Biology, Dr. Erin Knock, discusses the applications of in vitro model systems and demonstrates how ϳԹ’s tools can help overcome barriers to neural stem cell research. -
“Neurodegenerative Diseases” Featuring Dr. Clive SvendsenOn this episode of the Stem Cell Podcast, Dr. Clive Svendsen from Cedars-Sinai talks about using stem cells to model spinal muscular atrophy and the blood-brain barrier, and his cell-gene therapy trial for ALS. -
ϳԹ Journal Club: Mechanisms of Glioblastoma ResistanceDr. Jason Hamlin discusses the role of brain tumor stem cells in the development of glioblastoma treatment resistance -
How to Detect and Isolate Normal and Cancer Stem Cells Based on ALDH Activity with ALDEFLUOR™An innovative, antibody-free system to rapidly identify stem and progenitor cells of several tissue types, including a variety of cancer stem cells -
Optimization of ALDEFLUOR™ ProtocolLearn how ϳԹ' scientists doubled the signal strength in mammary epithelial cells with a few simple protocol modifications using ALDEFLUOR™ to detect Aldehyde Dehydrogenase bright (ALDHbr) cells -
Neural Induction of hPSCs Using the Embryoid Body MethodSTEMdiff™ Neural Induction Medium is a defined, serum-free medium for the efficient & reproducible derivation of neural progenitor cells
