“Development of the Heart, Lung, and Vasculature” Featuring Dr. Mingxia Gu
On this episode of the Stem Cell Podcast, Dr. Mingxia Gu from Cincinnati Children’s Hospital discusses developing lung organoids to study COVID-19, how multi-lineage organoids can mimic human tissues, and her lab’s motto to “move fast and break things.”
Dr. Mingxia Gu is an Assistant Professor of Pediatrics at Cincinnati Children’s Hospital. Her lab’s goal is to develop novel therapies for the regeneration of the heart, lung, and vasculature in patients with congenital cardiac and pulmonary defects. She talks about developing lung organoids to study COVID-19, how multi-lineage organoids can mimic human tissues, and her lab’s motto to “move fast and break things.”
Dr. Mingxia Gu is a vascular biologist utilizing iPSCs to model pulmonary hypertension and other disorders of the cardiovascular system. She is a new PI at Cincinnati Children's Hospital, a well-known powerhouse in organoid biology: a great fit for her research.
Dr. Arun Sharma, host
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This Episode's Stem Cell Roundup:
- – Metabolic bias induced by asymmetric apportioning of aged mitochondria leads to changes in cell fate and stemness.
- – Researchers performed whole genome sequencing on 143 readily-available hESCs, and found that a third of them shared sibling relationships.
- – Scientists developed a new single cell analysis platform designed for low cell-input samples
- – Researchers cryopreserved islets for nine months and implanted them into mice, leading to long-term glycemic control.
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