“Neurodegenerative Diseases” Featuring Dr. Clive Svendsen
On this episode of the Stem Cell Podcast, Dr. Clive Svendsen from Cedars-Sinai talks about using stem cells to model spinal muscular atrophy and the blood-brain barrier, and his cell-gene therapy trial for ALS.
Dr. Clive Svendsen is the Executive Director of the Regenerative Medicine Institute at Cedars-Sinai. His lab uses stem cells to develop models and treatments for neurodegenerative diseases. He talks about using stem cells to model spinal muscular atrophy and the , and his .
Dr. Clive Svendsen is an expert in the area of neurodegeneration, and has had a productive career modeling and developing potential cell-based therapeutics for various neurodegenerative diseases. His lab also focuses on organ-on-chip strategies for modeling physiological barrier functions, and has recently even delved into space biology!
Dr. Arun Sharma, host
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This Episode's Stem Cell Roundup:
- – Monocytes deposit migrasomes to promote angiogenesis in chick embryos.
- – Ras drives malignancy in squamous cell carcinoma through aberrant crosstalk between cancer stem cells and their microenvironment.
- – A three-dimensional extracellular matrix-rich environment preserves long-term feeder-free naïve hiPSC self-renewal.
- – Alzheimer’s disease brains have high proportions of neurons that express senescence markers.
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