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HLA molecules are heterogeneous membrane proteins that are critical for proper immune function. However, the diversity in HLA expression can lead to issues during organ transplantation as the transplanted tissue may be seen as foreign by the recipient immune system. Therefore, tissue transplantation labs typically perform HLA typing assays to determine which HLA subtypes are present on donor and recipient cells, as well as crossmatch assays to evaluate the degree of reactivity of donor cells to recipient anti-HLA antibodies.

Below is a collection of scientific resources for your HLA research.

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The Human Leukocyte Antigen (HLA) Complex

This wallchart provides an overview of the human leukocyte antigen (HLA) complex, HLA genes and nomenclature of HLA alleles.

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