Immune Cells
Genome Editing
Genome Editing of Immune Cells
CRISPR-Cas9 genome editing of immune cell types holds great therapeutic potential, but application of genome editing to primary human immune cells has been hampered by challenges in efficient delivery and expression of the CRISPR machinery. Explore our protocols and resources for information on how to overcome these barriers and perform high-efficiency genome editing of these difficult-to-manipulate cell types in your own lab.
Technical Bulletin
Evaluation of Genome Editing
Technical Bulletin
Genome Editing with Direct Cas9 RNP Delivery Design Considerations
Technical Bulletin
Genome Editing of Human Primary T Cells Using CRISPR-Cas9